The makers of Prostadine cite 30+ studies validating the advertised benefits of the formula. According to the official website, you can support significant benefits by taking Prostadine daily, with ingredients like iodine backed by considerable scientific evidence proving they work to support prostate health.
According to Dr. Gary Huber, prostate tissues have high concentrations of iodine. When you take an iodine supplement, a significant amount of that iodine travels to your prostate (or to other thyroid-rich tissues like breast and thyroid tissues). Some studies have linked iodine to a reduced risk of prostate cancer. As Dr. Huber explains, iodine can increase normal, natural cell death (apoptosis), helping old cells die and get replaced by new cells.
One study found a connection between iodine and the risk of thyroid disease and prostate cancer. Researchers found people with low levels of iodine tended to have a higher risk of cancer and disease than people with high levels of iodine. Each serving of Prostadine provides you with 275mcg of iodine, or 183% of your daily value. That’s a significant dose of iodine – especially since most people already get some amount of iodine in their diet.
The second largest ingredient in Prostadine is neem oil. Neem oil is rich with a natural chemical called nimbolide. Some research suggests neem plant extract can reduce prostate tumor growth. In this 2006 study, for example, researchers in India found neem oil had potent anticancer effects on prostate cancer cells, inducing cell death (apoptosis). A separate study reviewed additional evidence on neem oil, concluding that neem and its derivatives have therapeutic potential for treating prostate cancer. The makers of Prostadine make no claims about the formula treating prostate cancer or helping with cancer in any way; however, neem may support overall prostate health in various ways.
The only other ingredient with a significant dose in Prostadine is saw palmetto extract. Saw palmetto extract is one of nature’s best-known prostate supplement ingredients. Multiple studies have connected saw palmetto extract to prostate benefits, and saw palmetto remains popular in the natural health community for its connection to prostate health. In this 2014 study, for example, researchers told a group of 225 men to take saw palmetto extract or a placebo. Researchers found men significantly improved symptoms of BPH after 6 to 12 months of taking saw palmetto extract.
Nevertheless, not all studies on saw palmetto extract have shown a link to prostate health. A 2012 Cochrane review of 32 controlled trials involving 5,666 men, for example, found saw palmetto led to no improvement in urinary flow measures or prostate size in men with BPH – even at two to three times the normal dose. Another 2011 study involving 369 older men taking 320mg of saw palmetto extract per day found no benefits in urinary systems linked to BPH.
The other listed ingredients in Prostadine do not seem to have large enough doses to significantly impact human health. All other listed ingredients have just 5mg to 10mg of formula per serving of Prostadine.
Overall, Prostadine contains a blend of three popular prostate supporting ingredients, including iodine, neem, and saw palmetto extract. These three ingredients are popular in natural health for their effects on prostate health, and some studies show they can improve symptoms of BPH, support urinary function, and support overall prostate health in various ways.